PhD, Associate Professor A.N. Zakharova¹
PhD Yu.G. Kalinnikova¹
Postgraduate E.S. Negodenko¹
Postgraduate A.A. Orlova¹
Dr. Med., Professor L.V. Kapilevich^{1, 2
1}National Research Tomsk State University, Tomsk
²Siberian State Medical University, Tomsk

Objective of the present study was to develop and verify a model of cyclic training loads in application to small laboratory animals.
Methods and structure of the study. We developed an experimental facility to simulate cyclic running loads in different load modes, with different speeds of running and different pitch angles. The machine was tested on the mouse line C57BL/6 at the age of 12 weeks (n=60). The total duration of workload was 4 weeks, 6 running loads per week, 60 minutes each.
Results and conclusions. All mice performed the physical loads successfully. After the first insight into the test procedure, the animals completely familiarized themselves with the task, and on the second day performed the loads in full. There was no abnormal reaction in their behavior and functional state. No reduction of food or water intake was detected. No fatalities were reported during or after the tests either.
The authors conclude that the developed experimental model of execution of dosed physical loads for small laboratory animals can be recommended for a wide range of experimental studies in the field of sports physiology.

Keywords: physical load model, cyclic training load, treadmill, small laboratory animals.

References

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