Dr. Med., Professor V.N. Ananev¹
Dr. Med., Professor N.Y. Prokopyev²
G.V. Ananev³
PhD, Associate Professor V.V. Nasonov²
Dr. Med., Professor O.V. Ananeva^5
1State Scientific Center of the Russian Federation - Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
²University of Tyumen, Tyumen
³JSC "Pharmstandard", Moscow region, Dolgoprudny
⁴Tyumen State Medical University, Tyumen

Objective of the study was to assess the effect of regular dosed physical activity in men on the value of systemic arterial pressure due to the physiological mechanisms of working muscle hyperemia, leading to the normalization of high blood pressure.
Methods and structure of the study. To study the effect of sports activities on the value of systemic arterial pressure, a group of men (54 people) aged 55 to 70 years without bad habits was selected, who independently engaged in physical exercises (under the supervision of doctors) in health groups and did not take drugs according to their own convictions. During the experiment, men were asked to run daily with a pulse of no more than 85-110 beats / min for 60 minutes in the first half of the day and in the afternoon to take 5000-8000 steps for 60 days. To elucidate the mechanisms of the phenomenon of sympatholysis of an increase in blood flow during muscle contraction, physical activity was modeled on rabbits during electrical stimulation of the limb muscles and the introduction of adrenaline into the arteries.
Results and conclusions. Scientifically dosed physical activity leads to the expansion of the arteries of working muscles and helps to reduce and normalize elevated systemic blood pressure in men. In animal experiments, when modeling working muscle hyperemia, it has been proven that alpha-adrenergic receptors of arteries to adrenaline (sympatholysis) are blocked in working muscles, due to which blood flow increases and blood pressure decreases.

Keywords: men, normalization of blood pressure, physical activity, muscle working hyperemia, receptor mechanisms of muscle hyperemia.

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